Therapeutic controlled release
Micelle based therapeutics dissolution for local release.
We are using amphiphilic copolymer polyethers as structures that self assemble around body temperature. We have probed release of antibiotics and antimicrobials, chemotherapeutics, and other probiotics, embedded in these structures. We have an NIH proposal in review and a large review paper coming out
Injectable self-assembling gels
Relating to antibiotics, the notion of a flooding local infection areas are applicable to both joint replacement, perhaps general sepsis, and perhaps linked with surface infections arising from limb extension procedures. Since the self assembling gels based on micelle formation is a platform technology, the notion of swapping out antibiotics for another therapeutic might be just as relevant.